Xenical (orlistat) is a prescribed weight loss medication that is taken by mouth before, or up to one hour after consuming any meal containing fat. Xenical has been clinically proven to absorb up to 30% of fat from calories contained in the food that we eat—which our bodies would otherwise process and absorb into the system. When taken as directed by your doctor, Xenical can successfully prevent you from gaining extra fat, and when taken in combination with the proper diet and exercise Xenical has shown to help people shed the unwanted pounds and extra weight in a natural and healthy manner, and at surprisingly quick rate.
Only take Xenical as directed by your doctor. Xenical is intended to be taken by mouth with liquid before, during, or up to one hour following a meal that contains fat from calories. Xenical can be taken up to three times per day with each meal containing fat. If you miss a dosage of Xenical do not double-dose, simply take your next dose during the next meal that you consume which contains fat. Xenical is not to be taken more than three times per day, and furthermore there has not been any conclusive evidence that suggests by taking this medication more than three times per day it will have any additional weight loss effects. Always make sure to ask your doctor about any important dosing questions that you may have regarding the usage of this prescription drug.
Our digestive systems use enzymes called lipases to help break down, digest and absorb fat into the system. Xenical works by attaching to these lipases, and by not allowing them to break down all of the fat. In fact, Xenical allows for up to 30% of all fat consumed during each meal to be shed from the body through the bowels, and not absorbed and stored in the system.
There are countless advantages to using Xenical. For one, you can know that your body is working overtime to get rid of that excess fat you consume during each meal instead of storing it and gaining unwanted weight. You will begin to feel healthier with each passing day as you shed the weight using Xenical. Xenical does require a commitment on the part of patients. You must commit to eating healthier foods that contain no more than 30% calories from fat during each meal, in order to see the success you want to see from taking this prescribed weight loss drug.
Xenical does have some common and uncommon side effects which can occur from taking it that you should know about.
* Oily spotting in stool
* Excess gas
* More frequent bowel movements
* Oily discharge
* Inability to control bowel movements
* Brown and or orange colored oil in stool
* In rare cases, a very serious allergic reaction occurred including the following symptoms: shortness of breath, hives, swelling of tongue, lips or face and or closing of the throat—if you experience any of these rare yet very serious side effects STOP taking Xenical and seek immediate medical treatment.
It should also be noted that in most cases these common side effects occurred when patients taking Xenical consumed more than 30% calories from fat during a meal. Additionally, most of these side effects stopped occurring with continued usage of this drug.
Only your doctor will be able to tell you if Xenical is the right weight loss drug for your situation. Always consult with a physician before taking this or any other prescription drug. There are some people who may not be able to take Xenical including:
* People who suffer from chronic malabsorption syndrome
* People who suffer from gallbladder problems
* People who suffer from kidney stones
* People who suffer from bulimia
* People who suffer from anorexia
* People who suffer from diabetes
* Women who are expecting, pregnant or nursing
There are some people who will not be able to take Xenical if they are taking certain medications. Always make sure to consult with your physician and to tell them about ALL the drugs that you are currently taking, whether or not they are prescribed or if they are bought over the counter at a drugstore, to avoid any potential drug interactions. People who are currently taking the following drugs may not be able to take Xenical to treat their weight loss.
* Drugs containing warfarin
* Drugs containing cyclosporine
* Drugs containing atorvastatin (Lipitor)
* Drugs containing cerivastatin (Baycol)
* Drugs containing fluvastatin (Lescol)
* Drugs containing lovastatin (Mevacor)
* Drugs containing pravastatin (Pravachol)
* Drugs containing simvastatin (Zocor)
Important Patient InformationORLISTAT - ORAL (OR-li-stat) COMMON BRAND NAME(S): Alli, Xenical
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
USES: This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Taking orlistat can also help keep you from gaining back weight you have lost. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.
HOW TO USE: If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this medication. If your doctor has prescribed this medication, read the Patient Information Leaflet if available from your pharmacist before you start taking orlistat and each time you get a refill. Take this medication as directed by your doctor, by mouth with liquid sometime during each meal that contains fat or within 1 hour after the meal, usually 3 times daily. If you miss a meal or your meal contains no fat, skip that dose of the medication. To decrease the chance of unpleasant side effects, it is very important that no more than 30% of the calories in your diet come from fat. Your daily intake of fat, protein, and carbohydrates should be evenly spread over 3 main meals. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Because this drug can interfere with the absorption of certain vitamins (fat-soluble vitamins including A, D, E, K), a daily multivitamin supplement containing these nutrients is recommended. Take the multivitamin at least 2 hours before or 2 hours after taking orlistat (such as at bedtime). If you take cyclosporine, take it at least 3 hours before or after orlistat to make sure the full dose of cyclosporine is absorbed into your bloodstream. If you take levothyroxine, take it at least 4 hours before or after orlistat. You should see some weight loss within 2 weeks after you start orlistat. Tell your doctor if your condition does not improve or if it worsens.
SIDE EFFECTS: Changes in your bowel function often occur because of the unabsorbed fat. Fatty/oily stool, oily spotting, intestinal gas with discharge, a feeling of needing to have a bowel movement right away, increased number of bowel movements, or poor bowel control may occur. These side effects may get worse if you eat more fat than you should. If these effects persist or worsen, notify your doctor promptly. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Stop taking this medication and tell your doctor right away if any of these rare but serious side effects occur: symptoms of liver disease (such as persistent nausea/vomiting, severe stomach/abdominal pain, dark urine, yellowing eyes/skin), symptoms of kidney stones (such as back pain, pain when urinating, pink/bloody urine). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking orlistat, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain digestive problem (chronic malabsorption syndrome), a certain gall bladder problem (cholestasis), underactive thyroid (hypothyroidism), kidney stones/problems (such as calcium oxalate kidney stones, hyperoxaluria), certain eating disorders (anorexia nervosa/bulimia), HIV infection, seizures. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). If you are diabetic, weight loss may improve your blood sugar control. Be sure to check your blood sugar regularly and tell your doctor the results. Your doctor may need to adjust your diabetes medication, exercise program, or diet. This medication must not be used during pregnancy. Weight loss offers no potential benefit to a pregnant woman and may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor right away. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: "blood thinners" (such as warfarin), HIV medications (such as atazanavir, efavirenz, emtricitabine, lopinavir, ritonavir, tenofovir). If you are taking medications to treat seizures, orlistat may cause these drugs to not work as well. Stop taking orlistat and tell your doctor right away if your seizures are happening more often or are getting worse.
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
MISSED DOSE: If you miss a dose, take it as soon as you remember unless it has been more than 1-2 hours since your meal. In that case, skip the missed dose since most of the fat from your meal will already have been absorbed and the medication will not work. Do not double the dose to catch up.
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.
This product information is intended for United States residents only. Before prescribing, please refer to the patient information. You can view the document and also download it on your computer. You may also consider printing out a copy for yourself. View US Prescribing Information - PDF Version
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